I don't really ship it, to be perfectly honest. The only Mane Six ships I really have much support for are Flutterdash and Twidash, and both because I think they're cute rather than because I have any interest in seeing those relationships develop into romantic ones. Rarijack is cute but at the same time I'm really enjoying seeing how Spike's relationship with Rarity is developing. With that in mind, I'm not a Sparity shipper in that I would be severely peeved if it turns out that he and Rarity don't really work out as a couple, since relationships are dynamic and it can be just as interesting to see how certain relationships fail to work out as to see how others succeed.

But back to Twinkie. I don't really see how Twilight and Pinkie Pie have very good chemistry. But feel free to list examples. I'm sure after this weekend Twinkie shippers might have a lot more fuel for speculation, since Twilight and Pinkie are supposed to be key characters in the upcoming episode.